By Carole Gan
UC Davis microbiologists have analyzed swabs taken by astronauts on the International Space Station – and found pretty much the same types of microbes as in a home on Earth, according to an analysis published today (Dec. 5) in the journal PeerJ.
The International Space Station is interesting to scientists studying the microbial ecology of buildings because it is a “building” with very few ways to bring microbes in or out.
Citizen science and Project MERCURRI
The work was part of Project MERCCURI, a collaboration between UC Davis and other organizations including Science Cheerleader, a group of current and former professional cheerleaders pursuing careers in science and math.
By Diane Nelson
About 22,000 years ago, as the ice sheets that consumed much of North America and Europe began retreating, humans started to eat a fruit that today brings joy to millions of wine drinkers around the world: grapes.
People have been making wine from grapes for at least 8,000 years, but genetic evidence shows that humans influenced grape vines long before that (Gregory Urquiaga/UC Davis).
Researchers at the UC Davis School of Veterinary Medicine and Genome Center are taking part in an ambitious NIH initiative to make it easier for scientists to share research data and scientific tools online.
C. Titus Brown is associate professor in the UC Davis School of Veterinary Medicine and Genome Center.
“Harvesting the wealth of information in biomedical data will advance our understanding of human health and disease,” said NIH Director Francis S. Collins in a news release. “However, poor data accessibility is a major barrier to translating data into understanding. The NIH Data Commons Pilot Phase is an important effort to remove that barrier.”
Fifty-two newly discovered genes that are critical for hearing have been found by testing gene-modified ‘knockout’ mice. The newly identifed genes will provide insights into the causes of hearing loss in humans. The study published Oct. 12 in Nature Communications was carried out by the International Mouse Phenotyping Consortium (IMPC), which includes the Mouse Biology Program at the University of California, Davis.
Prof. Kent Lloyd, director of the UC Davis Mouse Biology Program, in the lab. Gene-edited and “knockout” mice have become a vital tool in biomedical research. (Karin Higgins/UC Davis photo)
Synthetic DNA Approach is Key to Startup’s New Drug
By Lisa Howard
The way Justin Siegel describes it, ordering synthetic DNA is almost as easy as ordering a pair of shoes online.
“You just type it in — or if the protein has been sequenced at one point, we can copy and paste — order it, and it shows up five days later.”
UC Davis chemist Justin Siegel is a co-founder of PvP Biologics. The company is developing a new treatment for celiac disease, an autoimmune disorder triggered by ingesting gluten. (UC Davis/Karin Higgins)
Initiative Aims to Support Responsible CRISPR Gene Editing
By Trina Wood
The federal Defense Advanced Research Projects Agency (DARPA) last week announced the Safe Genes program to explore innovative genetic techniques to support bio-innovation and combat biological threats. The effort, supported by a $65 million grant from DARPA over four years, aims to harness gene editing tools in a safe, responsible manner to maximize the benefits of these technologies while minimizing their inherent risks.
Aedes aegypti carries yellow fever, Zika and other viruses. (CDC photo)
By Ana Lucia Cordova-Kreylos
The UC Davis Office of Research this week (July 10) announced the launch of the Microbiome Special Research Program (SRP), designed to leverage and build upon the broad and deep expertise in microbiome science across the university.
“UC Davis has incredible breadth and depth in microbiome research with over 100 laboratories actively pursuing projects with links to agriculture, environment, energy and human and animal health,” said Cameron Carter, interim vice chancellor for research at UC Davis. “The decision to invest in a platform to empower these teams was obvious given our strength in these areas and our potential to charter new frontiers that address some of our world’s most pressing issues.”
By Diane Nelson
The bioinformatics company Illumina has donated a state-of the-art DNA sequencer to a global plant-breeding effort to fight malnutrition and poverty in Africa by improving the continent’s traditional crops. UC Davis is partnering in the African Orphan Crop Consortium, which is working to map and make public the genomes of 101 indigenous African foods.
These “orphan” crops are crucial to African livelihood and nutrition, but have been mostly ignored by science and seed companies because they are not traded internationally like commodities such as rice, corn, and wheat.