Researchers at UC Davis, the Boyce Thompson Institute (BTI) at Cornell University, the University of Minnesota and Iowa State University have received a four-year, $10.3 million “Insect Allies” award from the Defense Advance Research Projects Agency (DARPA) to engineer viruses carried by insects that can help in combatting disease, drought, and other yield-reducing stresses in maize.
Homologous Recombination Can Cause More Breaks As It Fixes Them
The traditional view of cancer is that a cell has to sustain a series of hits to its DNA before its defenses break down enough for it to turn cancerous. But cancer researchers have also found that cells can experience very rapid and widespread DNA damage that could quickly lead to cancer or developmental defects.
Now researchers at the University of California, Davis, have found that these complex chromosomal rearrangements can be triggered in a single event when a process used to repair DNA breaks, homologous recombination, goes wrong. The work is published Aug. 10 in the journal Cell.
Initiative Aims to Support Responsible CRISPR Gene Editing
By Trina Wood
The federal Defense Advanced Research Projects Agency (DARPA) last week announced the Safe Genes program to explore innovative genetic techniques to support bio-innovation and combat biological threats. The effort, supported by a $65 million grant from DARPA over four years, aims to harness gene editing tools in a safe, responsible manner to maximize the benefits of these technologies while minimizing their inherent risks.
By Ana Lucia Cordova-Kreylos
The UC Davis Office of Research this week (July 10) announced the launch of the Microbiome Special Research Program (SRP), designed to leverage and build upon the broad and deep expertise in microbiome science across the university.
“UC Davis has incredible breadth and depth in microbiome research with over 100 laboratories actively pursuing projects with links to agriculture, environment, energy and human and animal health,” said Cameron Carter, interim vice chancellor for research at UC Davis. “The decision to invest in a platform to empower these teams was obvious given our strength in these areas and our potential to charter new frontiers that address some of our world’s most pressing issues.”
By Kathy Keatley Garvey
A study of microbes that live in the nectar of flowers has turned up an unexpected result that challenges a common assumption in ecology.
It’s been widely assumed that the more easily organisms can disperse between habitats, the more similar the mix of species in those habitats will be.
By Dawn Rowe
The UC Davis Mouse Biology Program (MBP) has received an award of $414,000 from the National Institutes of Health to move towards sustainable, environment-friendly technology for its high-containment vivarium for mutant mice. The grant will also improve animal health and welfare, ergonomics for vivarium staff, and operational efficiencies.
Going ‘green” is a multi-step process that will take place over the next 12 months, and led by Kristin Grimsrud, associate director of vivaria and veterinary care for the program.
In this episode of our Three Minute Egghead podcast, UC Davis plant biologist Siobhan Brady talks about her work on roots.
Roots are the key innovation that allowed plants to conquer the land. They allow a plant to explore its environment, seeking out water and nutrients. A cell type within roots called xylem transports water and also provides support for land plants, allowing them to grow swiftly like a field of corn or reach towering heights of a sequoia.
By Karen Nikos-Rose
Are you the kind of person who, at a party, tends to be surrounded by friends in the middle of the crowd, or do you prefer to find a quiet corner where you can sit and talk? Recent work by scientists at UC Davis shows that wild baboons behave similarly to humans — with some animals consistently found in the vanguard of their troop while others crowd to the center or lag in the rear.
By Kathy Keatley Garvey
Rice farmers seeking to protect their crops from pests without high dependency on pesticides may want to consider the sustainable pest management practice known as the “banker plant system.”
First-of-its-kind research, published in Scientific Reports by a nine-member team including UC Davis agricultural entomologist Christian Nansen, indicated that attracting alternative hosts for parasitoids of rice insect pests can help protect a rice crop. The players: a grass species, a planthopper, and an egg parasitoid.
By Carlos Villatoro
Imagine a world where maladies such as cystic fibrosis, Huntington’s Disease, or sickle cell anemia no longer exist. While the U.S. is far from achieving this lofty goal, it recently came a step closer at the California National Primate Research Center (CNPRC), where scientists have efficiently used CRISPR/Cas9 technology to modify the genes of rhesus macaque embryos.
The research, recently published in the latest edition of Human Molecular Genetics, paves the way for future studies where the possibility of birthing gene-edited monkeys that can serve as models for new therapies is greatly increased.