by Greg Watry
Nearly 47 million people worldwide live with dementia, according to the Alzheimer’s Association. That number is expected to rise to 76 million by 2030. While there is no cure for dementia, scientists are investigating various drugs to help mitigate cognition loss associated with the condition.
UC Davis researchers propose that foods provide signals that influence the brain and other body systems.
When it comes to understanding and preventing age-related cognitive dysfunction, Professor Raymond Rodriguez, Department of Molecular and Cellular Biology in the College of Biological Sciences at UC Davis, looks to food for answers.
By Diane Nelson
About 22,000 years ago, as the ice sheets that consumed much of North America and Europe began retreating, humans started to eat a fruit that today brings joy to millions of wine drinkers around the world: grapes.
People have been making wine from grapes for at least 8,000 years, but genetic evidence shows that humans influenced grape vines long before that (Gregory Urquiaga/UC Davis).
Mars, Inc., UC Davis and partners have launched a crowdsourcing initiative to solve the problem of aflatoxin contamination of crops. A series of aflatoxin puzzles will go online on Foldit, a platform that allows gamers to explore how amino acids are folded together to create proteins. The puzzles provide gamers with a starting enzyme that has the potential to degrade aflatoxin. Gamers from around the world then battle it out to redesign and improve the enzyme so that it can neutralize aflatoxin. Successful candidates from the computer game will be tested in the laboratory of Justin Siegel, assistant professor of chemistry, biochemistry and molecular medicine at UC Davis.
Synthetic DNA Approach is Key to Startup’s New Drug
By Lisa Howard
The way Justin Siegel describes it, ordering synthetic DNA is almost as easy as ordering a pair of shoes online.
“You just type it in — or if the protein has been sequenced at one point, we can copy and paste — order it, and it shows up five days later.”
UC Davis chemist Justin Siegel is a co-founder of PvP Biologics. The company is developing a new treatment for celiac disease, an autoimmune disorder triggered by ingesting gluten. (UC Davis/Karin Higgins)
The government of Haiti recently announced a program to fortify wheat flour with iron and folic acid, following a recommendation by UC Davis researchers who calculated that adding these nutrients to wheat flour during milling would prevent infant deaths and improve the health especially of women and children.
Farmers in Haiti’s Artibonite Valley
The new Haitian program, known by its French acronym RANFOSE, is supported by the United States Agency for International Development (USAID). In addition to adding folic acid and iron to wheat flour, it will fortify vegetable oils with Vitamin A and salt with iodine. RANFOSE will increase the availability of high-quality, fortified staple foods across the country and expand the local production and importation of fortified foods, according to a US Embassy news release.
Could too much linoleic acid be making us sick?
By Diane Nelson
There are good and bad fats, nutritionists say. But not all polyunsaturated fats, the so-called good fats, are created equal. A food chemist at UC Davis is exploring whether eating too much linoleic acid—a type of polyunsaturated fat found mainly in vegetable oils—can cause chronic inflammation, headaches, and other health problems.
Food such as salmon that are high in omega-3 fatty acids may be healthier than foods with some vegetable oils. (RafalStachura/Getty Images)
Full post: Not All “Good Fats” Are Created Equal
(770 words, 2 images, estimated 3:05 mins reading time)
Key to Tea’s Benefits May Be in the Soil
By Becky Oskin
Tea has long been linked to human health benefits like preventing cancer and heart disease. But with hundreds of chemical compounds hidden in tea leaves, it is unclear which substances have the strongest effects.
The slew of “healthy” chemicals in tea varies with the variety of plant, how and where it is grown, and how the leaves are processed. Even soil bacteria contribute to a plant’s chemical profile, including its color, taste and aroma.
Full post: Microbes Could Bring Tea to California
(410 words, 1 image, estimated 1:38 mins reading time)
The Research Center of the Specialty Coffee Association (SCA) is teaming up with the UC Davis Coffee Center to embark on a two-year project to re-evaluate the scientific assumptions, measurement tools, sensory information, and – most importantly – consumer research that forms the foundation of the coffee industry’s fundamental understanding of coffee brewing.
Students in the UC Davis “Design of Coffee” class learn engineering principles from roasting and brewing coffee.
This research is underwritten with funding from Breville, which produces high-end appliances, including coffee and tea equipment.
Full post: Industry Supports UC Davis Coffee Research
(422 words, 1 image, estimated 1:41 mins reading time)
By Lisa Howard
Soil Actually Has a Microbiome
Gut bacteria have been getting a lot of attention lately (yogurt, anyone?) but it turns out the soil in your own back yard is teeming with microbial life. According to Kate Scow, a professor of soil science and microbial ecology at UC Davis, a quarter teaspoon of soil can easily contain a billion bacterial cells. And she estimates there can be 10,000 to 50,000 different taxa of microbes in a single teaspoon. Soil is one of the most complex and diverse ecosystems on the planet, and it is one that is essential for human life through all the functions it provides: the breakdown of organic materials, food production, water purification, greenhouse gas reduction, and pollution cleanup, just to name a few.
By Pat Bailey
A UC Davis-led study of nursing mothers in The Gambia shows how environment changes breast milk content
In a newly published study, UC Davis researchers and their colleagues, paint the picture of an elegant web of cause-and-effect that connects climate, the breast milk of nursing moms, gut microbes and the health of breast fed infants.
The research is part of a long-running. cross-disciplinary project at UC Davis studying milk and its role in nutrition. For example, last year UC Davis scientists and colleagues at Washington University St. Louis worked with both children and animal models to show how milk compounds could alter gut microbe composition and affect health. UC Davis researchers also led a consortium to study the “milk genome,” the collection of all genes related to producing milk.