Prozac Use in Children: Studying Side Effects of Fluoxetine in a Monkey Model

Fluoxetine (Prozac) is widely prescribed for depression, anxiety and other behavioral and psychiatric disorders and is approved for use in children. But little is known about the side effects of fluoxetine, part of a class of drugs called Selective Serotonin Reuptake Inhibitors (SSRIs) in pre-teen children.

Young monkeys

Rhesus macacque monkeys have a relatively long period of development before they reach sexual maturity. That makes them a useful model to study the possible side effects of Fluoxetine (Prozac) in children. (Photo by K. West, CNPRC)

Anxiety and Children with Fragile X Syndrome

By Kathleen Holder

Anxiety is a common problem for children and adults with fragile X syndrome, magnifying their struggles living with an inherited intellectual disability. New UC Davis research could lead to new ways to identify and treat their anxiety at a young age—even in infancy.

The study led by developmental psychologists Jessica Burris and Susan Rivera found that infants and young children with fragile X syndrome, unlike typically developing children, tend to have their attention specifically captured by angry faces rather than happy ones. That sort of “attentional bias” toward angry faces is a pattern associated with anxiety.