From Lab Fruit Flies to Mosquito Extermination in 30 Years

Louis Pasteur famously compared science and its application to a tree and it’s fruit. The path from a fundamental discovery to application can be a long and winding one, but rewarding none the less.

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Discoveries in basic genetics have now enabled scientists to wipe out lab populations of the malaria mosquito, Anopheles gambiae. (Anthony Cornel)

Professor Ken Burtis, faculty advisor to the Chancellor and Provost, recently came across an exciting example. Burtis was looking for a study for his first year seminar class when he found a paper from Andrea Crisanti’s lab at Imperial College London. Crisanti’s team was able to wipe out a lab population of Anopheles gambiae mosquitoes by introducing a disrupted gene for sex determination and using CRISPR “gene drive” technology to spread it through the population. Within eight generations, there were no female mosquitoes left for breeding.

Six Takeaways from the International One Health Congress

By Tracey Goldstein

I recently returned from the 2018 International One Health Congress(#IOHC) in beautiful Saskatoon, Canada. Insight, inspiration and networking were in abundance at the biennial conference, which drew more than 800 participants from 60 countries to hear renowned experts and researchers in One Health. It was a privilege to share the work of the UC Davis One Health Institute (OHI) and PREDICT.

Back in my office, many IOHC sessions and conversations remain top of mind. Here are my key takeaways:

UC Davis Joins Initiative to Fight Malaria in Africa

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Scientists hope to control the spread of malaria using genetically modified mosquitoes that are resistant to the parasite.

By Trina Wood

UC Davis vector biologist Greg Lanzaro is taking part in the newly-announced UC Irvine Malaria Initiative to genetically engineer new strains of mosquitoes to fight malaria in Africa. The project, led by UCI’s pioneering vector biologist Anthony James, will bring together experts in molecular biology, entomology, public health and community engagement from across the UC system.