Of Mice and…Gorillas? Mouse Gene Catalog as a Conservation Tool

Gorilla

Mice share a similar set of genes to humans and gorillas. A catalog of the functions of all mouse genes could help in conservation efforts for endangered species.

A new study from the International Mouse Phenotyping Consortium, which includes the UC Davis Mouse Biology Program, shows how the growing catalog of mouse genes could be applied to save endangered species. The paper was published May 24 in the journal Conservation Genetics.

Hear This: Knockout Mice Show Genes Linked to Deafness

Fifty-two newly discovered genes that are critical for hearing have been found by testing gene-modified ‘knockout’ mice. The newly identifed genes will provide insights into the causes of hearing loss in humans. The study published Oct. 12 in Nature Communications was carried out by the International Mouse Phenotyping Consortium (IMPC), which includes the Mouse Biology Program at the University of California, Davis.

Prof. Kent Lloyd, director of the UC Davis Mouse Biology Program, in the lab. Gene-edited and “knockout” mice have become a vital tool in biomedical research. (Karin Higgins/UC Davis photo)