Mice Help Find Gene for Bad Breath

An international team of researchers has identified a cause for chronic bad breath (halitosis), with the help of gene knockout mice from the UC Davis Mouse Biology Program. The results are published Dec. 18 in the journal Nature Genetics.

Prof. Kent Lloyd, director of the UC Davis Mouse Biology Program, in the lab. Gene-edited and “knockout” mice have become a vital tool in biomedical research. (Karin Higgins/UC Davis photo)

While most cases of bad breath are linked bacteria growing in the mouth, up to 3 percent of the population have chronic halitosis of no obvious cause.