By Jenna Gallegos
Scientists at the University of California, Davis have discovered that DNA sequences thought to be essential for gene activity can be expendable. Sequences once called junk sometimes call the shots instead.
Jenna Gallegos with an Arabidopsis thaliana plant. Sometimes called “thale cress,” Arabidopsis is a popular plant for laboratory studies.
Professor Alan Rose has been working for over two decades to unravel a mechanism called “intron-mediated enhancement.” I’m a graduate student in Rose’s lab, and we made an exceptional discovery in an unexceptional plant called Arabidopsis thaliana, or thale cress.
Represents Most Successful Group of Flowering Plants
By Pat Bailey
Today (April 12), UC Davis researchers announced in Nature Communications that they have unlocked a treasure-trove of genetic information about lettuce and related plants, releasing the first comprehensive genome assembly for lettuce and the huge Compositae plant family.
Lettuce belongs to a large Compositae family of plants. A lettuce flower shows the similarity to plants such as ragweed and sunflowers. (Gregory Urquiaga)
Garden lettuce, or Lactuca sativa, is the plant species that includes a salad bar’s worth of lettuce types, ranging from iceberg to romaine. With an annual on-farm value of more than $2.4 billion, it is the most valuable fresh vegetable and one of the 10 most valuable crops, overall, in the United States.
Applying mathematics to detect chemical weapons, hidden explosives or other threats is the goal of an ongoing project at the UC Davis Department of Mathematics, supported by grants from the National Science Foundation.
Blind deconvolution is a mathematical method to clarify a blurred image without knowledge of the original image, or how it was blurred. Top, original image; bottom, blurred image after blind deconvolution (Original image by Steve Byland).
Threat detection involves math at a range of levels, said Professor Thomas Strohmer, who leads the project. It can include quickly processing large amounts of data, coordinating multiple sensors, or extracting clarity from background noise.
Full post: NSF Grant Funds Math For National Security
(455 words, 1 image, estimated 1:49 mins reading time)
Possible new route to regenerating function lost in diabetes
In people with type I diabetes, insulin-producing beta cells in the pancreas die and are not replaced. Without these cells, the body loses the ability to control blood glucose. Researchers at the University of California, Davis have now discovered a possible new route to regenerating beta cells, giving insight into the basic mechanisms behind healthy metabolism and diabetes. Eventually, such research could lead to better treatment or cures for diabetes.
Sorghum is the fifth most important cereal in the world. In sub-Saharan Africa, many farmers rely on this grain for food and feed. But Striga, a parasitic weed, can have a devastating impact on crop yield. With a grant of $8 million from the Bill & Melinda Gates Foundation, an international team including UC Davis researchers will now explore the potential of soil microbes to offer crop protection. The Netherlands Institute of Ecology (NIOO-KNAW) is coordinating the five-year project.
A sorghum field infested with Striga (purple flowers). The parasitic plant destroys up to half of Africa’s sorghum crop. (Taye Tessema, Ethiopian Institute of Agricultural Research)
By Becky Oskin
Cyanobacteria, one of Earth’s oldest life forms, offer a promising new source of petroleum-free fuels and chemicals. However, economies of scale currently make it challenging for these tiny creatures to compete with fossil fuels. Now, scientists at UC Davis are closer to meeting these challenges with a new advance that improves the production and growth rate of cyanobacteria.
UC Davis chemist Shota Atsumi is engineering these cyanobacteria to produce biofuels. (Photo by T.J. Ushing)
Visiting scholar Masahiro Kanno, graduate student Austin Carroll and chemistry professor Shota Atsumi introduced new genetic pathways into cyanobacteria that could help make microbe-based chemical production systems smaller and easier to operate.
By Carlos Villatoro
The successful application of an alternative male contraceptive in rhesus macaque monkeys at the California National Primate Research Center is paving the way for human clinical trials.
For over a century, men who did not want to father a child had only one permament option for contraception. But according to the results of a study conducted at the California National Primate Research Center (CNPRC), there could be an alternative to a vasectomy that is as efficient and has the potential to be easily and successfully reversible.
Tests with rhesus monkeys show that Vasalgel shows potential as an alternative to vasectomy. (K. West, UC Davis)
By Pat Bailey
A UC Davis-led study of nursing mothers in The Gambia shows how environment changes breast milk content
In a newly published study, UC Davis researchers and their colleagues, paint the picture of an elegant web of cause-and-effect that connects climate, the breast milk of nursing moms, gut microbes and the health of breast fed infants.
The research is part of a long-running. cross-disciplinary project at UC Davis studying milk and its role in nutrition. For example, last year UC Davis scientists and colleagues at Washington University St. Louis worked with both children and animal models to show how milk compounds could alter gut microbe composition and affect health. UC Davis researchers also led a consortium to study the “milk genome,” the collection of all genes related to producing milk.
Where would we be without meiosis and recombination? For a start, none of us sexually reproducing organisms would be here, because that’s how sperm and eggs are made. And when meiosis doesn’t work properly, it can lead to infertility, miscarriage, birth defects and developmental disorders.
Neil Hunter’s laboratory at the UC Davis College of Biological Sciences is teasing out the complex details of how meiosis works. In a new paper published online Jan. 6 in the journal Science, Hunter’s group describes new key players in meiosis, proteins called SUMO and ubiquitin and molecular machines called proteasomes. Ubiquitin is already well-known as a small protein that “tags” other proteins to be destroyed by proteasomes (wood chippers for proteins). SUMO is a close relative of ubiquitin.
Full post: New Steps in the Meiosis Chromosome Dance
(809 words, 2 images, estimated 3:14 mins reading time)