By Diane Nelson
Our genes can influence how we respond to stress. Science shows that some people are more genetically predisposed than others to develop depression and anxiety in response to stressful situations.
UC Davis psychologists Johnna Swartz (left) and Jay Belsky have found that genetic traits that make people vulnerable to stress-related mental health problems, are also those best equipped to respond to positive interventions.
What’s more, researchers say that chronic exposure to stressful conditions—such as poverty, family discord, and poor nutrition—can alter the way genes behave in children and adolescents, making them more susceptible to depression, anxiety, and other negative effects of stress.
Scientists hope to control the spread of malaria using genetically modified mosquitoes that are resistant to the parasite.
By Trina Wood
UC Davis vector biologist Greg Lanzaro is taking part in the newly-announced UC Irvine Malaria Initiative to genetically engineer new strains of mosquitoes to fight malaria in Africa. The project, led by UCI’s pioneering vector biologist Anthony James, will bring together experts in molecular biology, entomology, public health and community engagement from across the UC system.
By Kathy Keatley Garvey
Rice farmers seeking to protect their crops from pests without high dependency on pesticides may want to consider the sustainable pest management practice known as the “banker plant system.”
Planting a mix of sesame and Leersia sayanuka grass at the edge of rice fields encourages insects that parasitize a rice pest, the Brown plant hopper. (Photo courtesy of Zhongxian Lu)
First-of-its-kind research, published in Scientific Reports by a nine-member team including UC Davis agricultural entomologist Christian Nansen, indicated that attracting alternative hosts for parasitoids of rice insect pests can help protect a rice crop. The players: a grass species, a planthopper, and an egg parasitoid.
Full post: Banker Plants Control Rice Pests
(421 words, 1 image, estimated 1:41 mins reading time)
By Carlos Villatoro
Imagine a world where maladies such as cystic fibrosis, Huntington’s Disease, or sickle cell anemia no longer exist. While the U.S. is far from achieving this lofty goal, it recently came a step closer at the California National Primate Research Center (CNPRC), where scientists have efficiently used CRISPR/Cas9 technology to modify the genes of rhesus macaque embryos.
The research, recently published in the latest edition of Human Molecular Genetics, paves the way for future studies where the possibility of birthing gene-edited monkeys that can serve as models for new therapies is greatly increased.
By Becky Oskin
To find evidence of life on Mars, scientists from UC Davis and the U.S. Geological Survey are chasing clues in Mars-like environments on Earth.
The environment at the Iron Mountain mine near Redding, Calif. is similar to Mars. Amy Williams, Towson University
The researchers hope to find rock patterns and textures that are uniquely linked to microscopic life such as bacteria and algae. “It’s challenging to prove that a mineral was made by a living organism,” said lead study author Amy Williams, an assistant professor at Towson University in Towson, Maryland. Williams led the research as a graduate student at UC Davis. Finding similar textures in Mars rocks could bolster confidence that microscopic shapes in Red Planet rocks were formed by living creatures.
By Kathy Keatley Garvey
Researchers in Professor Bruce Hammock’s laboratory at UC Davis are studying mechanisms involved in blocking angiogenesis — the formation of new blood vessels. The findings may lead to new methods for preventing cancer growth and targeting other diseases, the researchers report.
Postdoc Amy Rand is studying how certain fats can affect growth of blood vessels in tumors.
A recently-published study from Hammock’s lab describes a novel lipid-signaling molecule that can change fundamental biological processes involved in human health and disease. It builds on landmark research by the Judah Folkman laboratory of Harvard Medical School, which earlier showed that cutting off blood vessels that feed a cancerous tumor could stop its growth.
By Jenna Gallegos
Scientists at the University of California, Davis have discovered that DNA sequences thought to be essential for gene activity can be expendable. Sequences once called junk sometimes call the shots instead.
Jenna Gallegos with an Arabidopsis thaliana plant. Sometimes called “thale cress,” Arabidopsis is a popular plant for laboratory studies.
Professor Alan Rose has been working for over two decades to unravel a mechanism called “intron-mediated enhancement.” I’m a graduate student in Rose’s lab, and we made an exceptional discovery in an unexceptional plant called Arabidopsis thaliana, or thale cress.
Represents Most Successful Group of Flowering Plants
By Pat Bailey
Today (April 12), UC Davis researchers announced in Nature Communications that they have unlocked a treasure-trove of genetic information about lettuce and related plants, releasing the first comprehensive genome assembly for lettuce and the huge Compositae plant family.
Lettuce belongs to a large Compositae family of plants. A lettuce flower shows the similarity to plants such as ragweed and sunflowers. (Gregory Urquiaga)
Garden lettuce, or Lactuca sativa, is the plant species that includes a salad bar’s worth of lettuce types, ranging from iceberg to romaine. With an annual on-farm value of more than $2.4 billion, it is the most valuable fresh vegetable and one of the 10 most valuable crops, overall, in the United States.
Applying mathematics to detect chemical weapons, hidden explosives or other threats is the goal of an ongoing project at the UC Davis Department of Mathematics, supported by grants from the National Science Foundation.
Blind deconvolution is a mathematical method to clarify a blurred image without knowledge of the original image, or how it was blurred. Top, original image; bottom, blurred image after blind deconvolution (Original image by Steve Byland).
Threat detection involves math at a range of levels, said Professor Thomas Strohmer, who leads the project. It can include quickly processing large amounts of data, coordinating multiple sensors, or extracting clarity from background noise.
Full post: NSF Grant Funds Math For National Security
(456 words, 1 image, estimated 1:49 mins reading time)
Possible new route to regenerating function lost in diabetes
In people with type I diabetes, insulin-producing beta cells in the pancreas die and are not replaced. Without these cells, the body loses the ability to control blood glucose. Researchers at the University of California, Davis have now discovered a possible new route to regenerating beta cells, giving insight into the basic mechanisms behind healthy metabolism and diabetes. Eventually, such research could lead to better treatment or cures for diabetes.