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About Egghead

Egghead is a blog about research by, with or related to UC Davis. Comments on posts are welcome, as are tips and suggestions for posts. General feedback may be sent to Andy Fell. This blog is created and maintained by UC Davis University Communications, and mostly edited by Andy Fell.

Talk: Forecasting to prevent the next viral storm

Nathan Wolfe, Lorry I. Lokey Visiting Professor of Human Biology at Stanford University and Director of the Global Viral Forecasting Network Initiative will give a public talk at UC Davis on May 24, “Before it Strikes: Forecasting the Next Viral Storm.” His talk will begin at 4.10 pm in room 180, Medical Sciences C building on the UC Davis campus (near Tupper Hall and the Genome and Biomedical Sciences Facility).

Wolfe founded the Global Viral Forecasting Network Initiative in 2007 with the goal of developing an early warning system for disease pandemics by monitoring the transmission of diseases from animals to humans. Most major human diseases, for example HIV, begin in animals and spread to humans, especially where people are constantly exposed to wild and domestic animals. The GVF aims to detect such transmission before diseases become established in humans.

Wolfe is a Fulbright fellow, was awarded the NIH International Research Scientist Development Award in 1999, and the prestigious NIH Director’s Pioneer Award in 2005. He is currently a National Geographic Emerging Explorer and was named one of the World Economic Forum’s Young Global Leaders. He was recognized as one of Popular Science’s ‘Brilliant 10’ and Rolling Stone’s ‘Top 100 Agents of Change.’ He serves on the editorial board of EcoHealth and Scientific American.  Time Magazine named him one of the 100 most influential people in the world in 2011.

Wolfe’s talk is sponsored by the UC Davis College of Biological Sciences through the Storer Life Sciences Endowment.

Get your solar glasses, get ready for the May 20 solar eclipse!

On May 20th, northern California will be treated to an eclipse of the Sun as the moon’s shadow sweeps across the Earth. Best views of the event will be a bit north of Davis, closer to Redding where a total eclipse should be visible. The eclipse will begin about 6.20 pm Pacific Time and last for about four minutes.

This is an annular not a total eclipse, so even in the best location, a rim of the Sun will be visible around the Moon. That’s because the size of the Moon’s shadow varies a bit depending on the exact distance between the Earth and Moon.

“Eclipses are like the birth of a baby — they come with much anticipation and excitement, but may require special equipment, are all different, and the differences are usually important,” said UC Davis opthmalologist Ivan Schwab.

“This can be fun, but it does mean a bit of warning. It means that from Sacramento or Davis, an observer will never see a complete eclipse. It is never safe to view the sun partially eclipsed without protective eye wear,” Schwab said in an email. “Eclipse glasses can be worn and the eclipse can be safely viewed with these.”

As it happens, the UC Davis Geology Club is selling certified eclipse-viewing glasses at $2 a pair, three pairs for $5. If you want to order in bulk, further discounts are available, according to club co-president Kevin Delano. The club will deliver bulk orders in the Davis area, Delano said.

You can also use the glasses to view another, rarer astronomical event — the transit of Venus on June 5th, when the planet Venus will cross the Sun (from our point of view). The next transit of Venus will not occur until 2117.

To order glasses, contact Savannah Lisle, sllisle@ucdavis.edu. Proceeds go to the Geology Club.

Do NOT attempt to view the Sun through pinhole glasses, regular sunglasses or other makeshift glasses, Schwab warned.

“Don’t play with the potential of visual damage,” he said.

The Geology Club is not planning an event, Delano said, but does have information on where to go to best see the eclipse (Redding, Tahoe, Chico). However, geology professor Qing-Zhu Yin is giving a public talk on the Lotus Valley meteorite in Coloma on the evening of May 20, and an eclipse viewing will be held outside the venue immediately beforehand.

More about solar eclipses from Space.com

NASA page on May 20 eclipse

(Annular eclipse image from NASA Hinode satellite)

Public talk on the Lotus Valley meteorite — plus solar eclipse viewing!

UC Davis geology professor Qing-Zhu Yin will give a public talk, “The “Lotus Valley” Meteorite: What does it mean to science? What does it mean to our valley? What can it mean to you?” on Sunday, May 20.

Where: Gold Trail Grange #452, 319 State Highway 49

Coloma, CA 95613 (located within Marshall Gold Discovery State Historic Park)

Time: 7:00 p.m. – 8:00 p.m. (Free Parking at Sutter’s Mill Parking Lot next door)

In this general public talk, Dr. Yin will review what scientists could learn about the origin of our solar system from meteorites like the one that fell in Lotus Valley; why scientists need a lot more materials; how to identify the general features of these carbonaceous chondrites in the field, with examples from Lotus Valley fall; how to handle the sample for safe storage, etc. followed by a brief question-and-answer session.

Coincidentally, on May 20, the Annular Solar Eclipse occurs at 6:20 p.m. Lotus is well within 93 percent totality of view. Join Dr. Yin at 6:00 p.m. near the Grange for the eclipse viewing prior to the presentation on the meteorite.

Qing-Zhu Yin received his Ph.D. from the Max-Planck-Institute for Chemistry/Johannes Gutenberg University in Mainz, Germany and worked at Harvard University before joining UC Davis in 2003. He recently co-authored a book for lay readers, “Earth: Its Birth and Growth,” published by Cambridge University Press, 2012.

Hunting meteor fragments, older than the Earth

The minivan-sized meteorite that broke up over the Sierra on Sunday, April 22 was not just any old space rock. It was one of the rarest types of meteorites to fall to Earth — a carbonaceous chondrite, the earliest solid material to form in our Solar System more than four and a half billion years ago, before the planets, including the Earth, formed.

Carbonaceous chondrite meteorite

If its age and identity are confirmed, this meteorite could turn out to be one of the most scientifically important to fall to Earth since the late 1960s, says UC Davis geology professor Qing-zhu Yin. Which explains why Yin’s out-of-office email currently reads, “Gone meteorite hunting.”

Yin’s lab at UC Davis is one of a few in the country with the equipment to analyze and accurately date the meteorite, which may contain carbon, water and even simple sugars — the basis of life. He hopes to collect as many fragments as possible for scientific analysis.

Carbonaceous meteorite

These primitive meteorites provide a glimpse into the first few tens of millions of years of the solar system’s history, Yin said. They contain grains that would predate our solar system, representing ejecta from nearby stars before our solar system was born over four and a half billion years ago.

Yin is asking locals and visitors to help his team track the meteorite, by recording the GPS coordinates of any fragments, and recover pieces. The main area of search is the Lotus valley, near Coloma.

“I have been in the field to reach out to the local community to help to recover as much materials as we can,” Yin said in an email. “They longer the material stays in the field, the more likely its scientific value being degraded.”

Yin said he’s also concerned that people might be using hand magnets on potential meteorite fragments. Magnets won’t help much with identifying the meteorites, he said, but could scramble the natural magnetic signals before they can be analyzed.
“I also want to express my sincere thanks to the local community for their outpouring support and generosity in this recovery effort and their genuine interests and their collaboration with UC Davis,” Yin said.

I have interviewed and talked to many people over the past weekend. I witnessed such an incredible display of warm, genuine hospitality to me and my students and postdocs. It amazes me that some locals took a group of complete strangers into your home with open arms and allowed them to search their property, while providing food, drink and company in the mean time…My students and I were moved beyond words by everything the Lotus community have done for us and find it difficult to adequately express our thanks to them. We are confident that the friendship and strong community support will help us to find a lot more of these materials in the near future.

I am confident that this back bone support from the local community will help realize the materials’ full scientific values eventually by the world scientific community at large, and UC Davis in particular (as the fireball and meteorite fall practically occurred in our backyard).

How to spot a meteorite: 

  • Black-greyish look, with a molten glassy fusion crust with goose bumps, and often with cracks
  • If pieces have broken off, the interior should show some specks of minerals — those are the first solid condensates of our solar system
  • They should be distinct from local rocks and surrounding environment.

Reach Professor Yin at: qyin@ucdavis.edu.

 

 

Vice Chancellor for Research elected to National Academy of Sciences

Harris Lewin, vice chancellor for research and professor of evolution and ecology at the University of California, Davis, has been elected to the National Academy of Sciences, one of the highest honors given to a scientist or engineer in the United States. Including Lewin, 21 UC Davis faculty are members of the academy.

“I am grateful to all those institutions, and the individuals within them, who enabled me to maximize the extraordinary opportunities presented by more than 30 years in science,” Lewin said. “In particular, I must thank the University of Illinois at Urbana-Champaign for allowing me the freedom to explore and to create; my family and mentors; and the many graduate students, postdocs and staff who are the primary reasons for my success.

“Special appreciation goes to my colleagues here at UC Davis, who exemplify excellence at every level, and who have supported me in my transition to the faculty and administration.”

Throughout his career, Lewin has been deeply involved in interdisciplinary research that has the potential to move from the laboratory to the marketplace, where it can help solve real-world problems. As a graduate student at UC Davis, he discovered genetic factors linked to disease resistance in cattle, leading to a patent on a screening test for cattle resistance to leukemia viruses. After graduating from UC Davis in 1984 with a doctorate in immunology, he moved to the University of Illinois Urbana-Champaign, where he was founding director of the Institute for Genomic Biology. He is widely known for his work in mammalian genomics, especially in livestock, and he played a leading role in the sequencing of the bovine genome.

Lewin returned to UC Davis in 2011 as vice chancellor for research. In that position, he oversees the Office of Research, which is responsible for organizing and promoting research on campus; managing grant applications; and overseeing intellectual property, technology transfer and efforts to translate UC Davis discoveries into new companies and products. Lewin’s office is also responsible for interdisciplinary Organized Research Units, research programs and facilities, such as the Institute for Transportation Studies, John Muir Institute of the Environment, Biotechnology Program and the Crocker Nuclear Laboratory.

Lewin is holder of the Robert and Rosabel Osborne Endowed Chair and Professor in the department of Evolution and Ecology, one of the top ranked departments in the country. He is also a member of the UC Davis Genome Center where he has a laboratory and is continuing his research on genome evolution.

In 2010-11, UC Davis received $684 million in funds to support research. According to a survey by the National Science Foundation, UC Davis ranks 16th in the nation in university research and development expenditures.

Chancellor Linda P. B. Katehi has set a goal of increasing the campus’s research budget to $1 billion, and Lewin has taken steps to help achieve that goal, including streamlining processes in the Office of Research and offering more support for interdisciplinary groups of faculty seeking to apply for large, multimillion-dollar grants.

The Office of Research recently announced the Interdisciplinary Frontiers Program, which will award grants of up to $1 million to faculty in science, engineering, arts and humanities as “seed money” to launch projects that can later compete for funding from external sources.

In 2011, Lewin was co-recipient of the prestigious Wolf Prize in Agriculture for his work on genetics, genomics and disease resistance in cattle. He also is a member of the Royal Swedish Academy of Agriculture and Forestry and a fellow of the American Association for the Advancement of Science.

Lewin and 83 other new members will be inducted into the National Academy of Sciences next April during its 150th annual meeting in Washington, D.C.

The National Academy of Sciences is a private, nonprofit honorific society of distinguished scholars engaged in scientific and engineering research, dedicated to the furthering of science and technology and to their use for the general welfare. Established in 1863, the academy has served to “investigate, examine, experiment, and report upon any subject of science or art” when called upon to do so by any department of the government. For more information, or for the full list of newly elected members, visit http://www.nasonline.org/.

Two from UC Davis to give Harvey lectures

Two faculty from the UC Davis College of Biological Sciences have been selected by the Harvey Society of New York to give Harvey lectures this year. Each year, the Society selects seven of the world’s leading biomedical researchers to give a free public talk at the Rockefeller University in New York. The collected lectures are published in book form every year. Most Nobel laureates in Physiology or Medicine have presented Harvey lectures, according to the Society.

Stephen Kowalczykowski, distinguished professor in the Department of Microbiology, gave his lecture, “Watching Individual Proteins Working on Single Molecules of DNA: From Biophysics to Cancer,” March 15. Professor Jodi Nunnari, chair of the Department of Molecular and Cellular Biology, will give a talk on “The Behavior of Mitochondria” May 17.

The Harvey Society was founded in 1905 by a group of New York scientists and physicians to forge a closer relationship between practical medicine and laboratory experiments. It is named after William Harvey, 1578-1657, the English physician who first proposed that the heart pumps blood around the body.

“Plant pharma” moves forward

Ventria Bioscience, based in Fort Collins, Colo. with manufacturing facilities in Kansas, has announced a  successful completion phase 2 clinical trial of its lead therapeutic candidate, VEN100, which is based on an antibacterial compound from human breastmilk grown in genetically modified rice plants.

Ventria was founded in 1993 by Ray Rodriguez, professor of molecular and cellular biology at UC Davis, and the company’s products are rooted in technology developed in Rodriguez’ lab at UC Davis. The company later relocated out of California. Rodriguez remains as chairman emeritus of the company.

The study was conducted by a team of investigators from Johns Hopkins University. The randomized, double-blind, placebo-controlled study tested the safety and tolerability of VEN100 and its ability to reduce the incidence of antibiotic-associated diarrhea (AAD) in high-risk patients. Patients treated with VEN100 were about half as likely to develop diarrhea during antibiotic treatment, they found. VEN100 was also found to be safe and well tolerated, with no observed adverse events in the study.

Antibiotic-associated diarrhea is a common adverse effect of broad-spectrum antibiotics, occurring in as many as 25 percent of patients taking these drugs. AAD can be mild in otherwise healthy adults but can become severe and life threatening in high-risk patients including elderly, immune-compromised, or otherwise vulnerable patient groups. While Clostridium difficile is a known etiologic agent for diarrhea, C. difficile infection explains less than half of all AAD cases. The standard treatment — more antibiotics.

More: News release from Ventria Bioscience; original research paper

South Pole Telescope homes in on dark energy, neutrinos

South Pole Telescope

Astronomers are using the South Pole Telescope to probe the Cosmic Microwave Background.

Data from the new 10-meter South Pole Telescope is providing new support for the most widely accepted explanation of dark energy, the source of the mysterious force that is responsible for the accelerating expansion of the universe.

The results also are beginning to hone in on the masses of the neutrinos, the most abundant particles in the universe, which until recently were thought to be without mass.

“It is astounding how SPT measurements of the largest structures in the universe lead to new insights on the evasive neutrinos,” said Lloyd Knox, professor of physics at UC Davis and member of the SPT collaboration. Knox will also highlight the neutrino results in his presentation on Neutrinos in Cosmology at a special session of the American Physical Society in Atlanta on Tuesday April 3.

Also speaking at the meeting will be UC Davis physicist Robert Svoboda, who will be giving the meeting an update on what we know about neutrinos and how we know it.

Constructed in the Antarctic summer of 2006-7, the South Pole Telescope operates at microwave wavelengths, taking pictures of the Cosmic Microwave Background (CMB) — how the universe looked very shortly after the Big Bang. The new data combines measurements from the SPT and orbiting X-ray telescopes.

As the light from the CMB passes through galaxy clusters, the clusters leave “shadows” that allow astronomers to identify the most massive clusters in the universe. That means that they can study how physics works at an enormous scale, and in turn allows them to make inferences about dark energy and the mass of neutrinos.

The preliminary data strongly support Albert Einstein’s cosmological constant, the leading model for dark energy.

“With the full SPT data set we will be able to place extremely tight constraints on dark energy and possibly determine the mass of the neutrinos,” said Bradford Benson, a postdoctoral scientist at the University of Chicago’s Kavli Institute for Cosmological Physics. Benson presented the latest findings on Sunday, April 1, at the APS meeting.

In the late 1990s, astronomers discovered that the expansion of the universe appeared to be accelerating instead of slowing down as predicted. “Dark energy” was the name given to an invisible, pervasive force throughout the universe that causes this acceleration.

This force could be the manifestation of Einstein’s cosmological constant, which effectively assigns energy to empty space, even when it is free of matter and radiation. Long before cosmic acceleration was discovered, Einstein introduced the cosmological constant into his theory of general relativity to accommodate a stationary universe, the dominant idea of his day. He later called it his “greatest blunder.”

The number of galaxy clusters that formed over the history of the universe is sensitive to the mass of the neutrinos and the influence of dark energy on the growth of cosmic structures. First proposed in 1920 and detected in 1955, the mass of neutrinos is unknown: but if they are too massive they would significantly affect the formation of galaxies and galaxy clusters, Benson said.

The SPT team has now placed tight limits on the neutrino masses, yielding a value that approaches predictions stemming from particle physics measurements.

More: news release from the South Pole Telescope collaboration (via Sciencedaily).

UC Davis magazine: Entrepreneurs, guns, domes

The Spring issue of UC Davis Magazine is on its way out to alumni and parents, and available online at the magazine’s website and in a new online “zmag” format.

The cover story of this issue, by Clifton Parker, is on campus entrepreneurship and efforts to promote innovation — how scholars and researchers are bridging the gap between campus and the marketplace with collaborations, patents and startup companies.

Clifton also reports on a new lease of life for Baggins End, the student cooperative housing also known as “The Domes.” The funky housing had been set to close until a new agreement was signed with the Solar Community Housing Association to manage the neighborhood.

In a very timely article, Sasha Abramsky profiles Garen Wintemute, a UC Davis emergency physician who has dedicated his career to an uphill struggle against the proliferation of guns and gun violence.

Plus news, letters, class notes from alumni, sports, an update on the Campaign for UC Davis, and some advice from Robin DeRieux on kitchen survival for students.

 

 

Oaxaca earthquake, one day later

A major earthquake struck Mexico just after 11 a.m. Pacific Time yesterday. Initial reports put the magnitude at 7.9 and relatively close to the surface, which would be a very serious earthquake. However, news reports from Mexico City and then other cities including Oaxaca and Acapulco showed relatively minor damage and few casualties, and the US Geological Survey later downgraded the magnitude to 7.4.

“It’s a good example of the fog of information after an event like this,” said UC Davis geologist Michael Oskin. “It went from 7.9, shallow (10km) and thus a high destructive potential to a 7.4, deep (20 km or deeper, I suspect) and unsurprising event on the subduction interface.”

A subduction interface is where one continental plate is sliding below another one and plunging into the Earth.

The area affected by the earthquake is wet and mountainous with a mixture of farmland and forest, Oskin said.

John Rundle, a professor of geology and of physics at UC Davis who studies earthquakes and earthquake forecasting, noted that while early reports showed relatively minor damage in the big cities, there might be more damage near the epicenter where construction techniques are likely to be poor.

It is also possible that a lot of damage to buildings might not become evident until  structural engineers carry out checks. This unseen damage can substantially increase the costs of an earthquake even if few lives are lost.

More:

KeckCAVES mapping Baja earthquake with virtual reality

John Rundle’s earthquake underground blog