Egghead is a blog about research by, with or related to UC Davis. Comments on posts are welcome, as are tips and suggestions for posts. General feedback may be sent to Andy Fell. This blog is created and maintained by UC Davis University Communications, and mostly edited by Andy Fell.
Stress in early life affects social behavior in adult zebra finches.
A new study shows that young birds raised under stressful conditions leave home earlier and develop a wider social network.
The paper co-authored by Damien Farine, now a post-doctoral researcher at the University of California, Davis, anthropology department, Neeltje Boogert, University of St Andrews, and Karen Spencer, Oxford University, was published in Biology Letters Wednesday, Oct. 29.
The researchers found that zebra finch chicks stressed during early development showed more independence from their parents, associated more randomly with other members of their flock and were less choosy about the birds they fed alongside.
“Stress is a possible mechanism to allow birds to try alternative strategies,” Farine said. “If you get a lot of this stress happening you may see them doing behaviors they have done before including widespread dispersals. When we see birds popping up in places they’ve not been before it might have something to do with stressful development. This could thus have major implications for maintaining locally-adapted behaviors and genetic structure across different sub-populations.”
Wild birds secrete a stress hormone when faced with food scarcity, predators or competition. The researchers artificially increased stress hormone levels in zebra finch chicks and tested how this affected their foraging behavior. The birds’ were monitored in aviaries where the stressed chicks and their families could visit bird feeders at any time and with any other birds. Each bird was fitted with a chip that recorded each time a bird visited one of the feeders over the course of five weeks.
Since 1963, UC Davis and Lawrence Livermore National Laboratory (LLNL) scientists and engineers have conducted joint interdisciplinary research that leverage the strengths of both institutions to address a variety of critical societal problems. Over the last year, leaders from LLNL and UC Davis have been working together to develop mechanisms that reinvigorate and deepen the partnerships between the institutions. Several joint faculty and lab researcher workshops have taken place over the last few months to identify and develop new topical areas of common interests. A number of joint grant proposals to federal funding agencies have been submitted and work is ongoing to identify funding mechanisms that facilitate additional collaborations.
As a component of this initiative, a Joint UCD-LLNL Graduate Mentorship Award program has been established. This program was created to provide a unique opportunity for graduate students to experience the complimentary research environment of both a leading university and a national laboratory during their PhD studies. The Mentorship Awards provide funding for up to three years of financial support for the graduate student. Graduate students will engage in research activities at both Livermore and Davis campuses under the joint supervision of the UC Davis faculty mentor and the LLNL staff scientist or engineer.
A Call for Proposals was issued through the UC Davis Office of Research, eliciting 25 submissions. Proposals were reviewed by independent peer review, following a process coordinated by LLNL and UC Davis. The quality of proposals was viewed as being uniformly high, with the following projects selected to receive funding in this first round:
Efficient Simulations for a Large-Scale Model of Cardiac Rhythms
UC Davis Co-Principal Investigator: Timothy Lewis, Professor of Mathematics
LLNL Co-Principal Investigator: David Richards
Engineered Nanostructure for Regulation of Cellular Signaling Cascades
UC Davis Co-Principal Investigator: Gang-yu Liu, Professor of Chemistry
LLNL Co-Principal Investigator: Ted Laurence
Ultralow Density Metal Foams for High Energy Density and Advanced Materials Research
UC Davis Co-Principal Investigator: Kai Liu, Professor of Physics
LLNL Co-Principal Investigator: Jeff Colvin
Rare Event Detection: Neutrinos and Dark Matter
UC Davis Co-Principal Investigator: Robert Svoboda, Professor of Physics
LLNL Co-Principal Investigator: Adam Bernstein
Funding for this program was provided by the University Relations and Science Education Group, LLNL, the UC Office of the President Laboratory Management Office, and UC Davis Office of Research.
Three UC Davis graduate students are among 105 to receive Science To Achieve Results (STAR) fellowships from the Environmental Protection Agency. The STAR fellows will receive a maximum funding of $42,000 a year for up to two years for doctoral students.
The UC Davis recipients and their projects are: Rachel Wigginton, “Predicting Return of Ecosystem Services Based on Impacts of Invasive Ecosystem Engineers;” Matthew Whalen, “Biodiversity of native and invasive suspension feeders affects water quality and potential for harmful algal blooms” and Kelly Gravuer, “Maintaining ecosystem function under climate change: Understanding and managing plant-soil microbe community dynamics.” All three are doctoral students.
“These fellowships are helping our next generation of scientists and engineers earning advanced degrees in environmental sciences conduct cutting edge research,” said Lek Kadeli, Acting Assistant Administrator for EPA’s Office of Research and Development in a news release. “Through this support, EPA is ensuring that the United States will have the scientific knowledge to meet future environmental challenges, which will strengthen our nation’s economy and security, while better protecting our health and environment in addition to combating climate change.”
Spectacular eruptions at Bárðarbunga volcano in central Iceland have been spewing lava continuously since Aug. 31. Massive amounts of erupting lava are connected to the destruction of supercontinents and dramatic changes in climate and ecosystems.
New research from UC Davis and Aarhus University in Denmark shows that high mantle temperatures miles beneath the Earth’s surface are essential for generating such large amounts of magma. In fact, the scientists found that the Bárðarbunga volcano lies directly above the hottest portion of the North Atlantic mantle plume.
“From time to time the Earth’s mantle belches out huge quantities of magma on a scale unlike anything witnessed in historic times,” Lesher said. “These events provide unique windows into the internal working of our planet.”
Such fiery events have produced large igneous provinces throughout Earth’s history. They are often attributed to upwelling of hot, deeply sourced mantle material, or “mantle plumes.”
Recent models have dismissed the role of mantle plumes in the formation of large igneous provinces, ascribing their origin instead to chemical anomalies in the shallow mantle.
Holuhraun fissure eruption on the flanks of the Bárðarbunga volcano in central Iceland on Oct. 4, 2014, showing the development of a lava lake in the foreground. Vapor clouds over the lava lake are caused by degassing of volatile-rich basaltic magma. (Photo: Morten S. Riishuus, Nordic Volcanological Institute)
Based on the volcanic record in and around Iceland over the last 56 million years and numerical modeling, Brown and Lesher show that high mantle temperatures are essential for generating the large magma volumes that gave rise to the North Atlantic large igneous provinces bordering Greenland and northern Europe.
Their findings further substantiate the critical role of mantle plumes in forming large igneous provinces.
“Our work offers new tools to constrain the physical and chemical conditions in the mantle responsible for large igneous provinces,” Brown said. “There’s little doubt that the mantle is composed of different types of chemical compounds, but this is not the dominant factor. Rather, locally high mantle temperatures are the key ingredient.”
The research was supported by grants from the US National Science Foundation and by the Niels Bohr Professorship funded by Danish National Research Foundation.
The fellowships are intended to give early-career scientists the freedom and flexibility to “think big” and explore new ideas and approaches.
Ramirez’ research focuses on how species adapt to each other as they evolve. Evolutionary biologists have long recognized that interactions between species play a central role in creating biological diversity. However, exactly how ecological pressures and genetics combine so that species co-evolve and adapt to each other is not well understood.
Ramirez’s research uses approaches from genetics, ecology and physiology to investigate bees and orchids have evolved together and adapted to each other. His research team is studying a group of bees called the orchid bees. This particular group of bees visits orchids — as well as other plant sources — to collect floral scents that the males present to females during courtship display. The orchids have evolved such degree of specialization to attract male bees that the plants exclusively depend on scent-seeking males for pollination.
Orchid bees and the plants they visit are highly dependent on each other.
Biologists have been puzzling over pollination for a long time: Charles Darwin and Alfred Russell Wallace worked on the problem, proposing that flowers and pollinators engaged in a race that resulted in deeper flowers and pollinators with longer noses. In fact, more than 80 percent of the world’s flowering plants depend on insects for pollination.
Previous recipients of Packard Fellowships at UC Davis are Professor Matthew Augustine, Department of Chemistry, and Professor Matthew Franklin, Department of Computer Science.
This week, an international team of researchers, led by the Chinese Academy of Agricultural Sciences in Beijing, is publishing in the journal Nature Genetics a brief genomic history of tomato breeding, based on sequencing of 360 varieties of the tomato plant.
Analysis of the genome sequences of these 360 varieties and wild strains shows which regions of the genome were under selection during domestication and breeding. The study identified two independent sets of genes responsible for making the fruit of modern commercial tomatoes 100 times larger than their wild ancestors.
An important finding is that specific regions of the tomato genome were unintentionally depleted in genetic variation: for example, in DNA around genes conferring larger fruit size or genes for resistance to diseases afflicting tomato plants.
These stretches of genetic uniformity illustrate the need to increase overall genetic diversity in modern varieties and highlight the important role that the Rick Tomato Genetics Resource Center and similar collections play in housing much of the genetic variability that will be critical for future breeding and research on tomato.
The 2014 Nobel Prize in Physiology or Medicine has been awarded to three neuroscientists, John O’Keefe, May-Britt Moser and Edvard I. Moser, for their discoveries of brain cells that allow us to make sense of place and location and navigate our environment.
In 1971, O’Keefe, then working at University College London, identified “place cells” in an area of the brain called the hippocampus. In rats, specific place cells activated when a rat was in a specific location, making up a map of the room inside the rat’s brain.
More than 30 years later, the Mosers discovered “grid cells,” that allow our brains to create coordinates and navigate between points.
“It is incredibly exciting that the Nobel committee has chosen to recognize and honor the seminal work of John O’Keefe and Edvard and May-Brit Moser,” Ekstrom said in an email. “Their work has completely changed our perspective on the interface between brain and behavior, providing a critical and previously non-existent link between the activity of individual neurons and higher order cognition.”
Their work demonstrates that changes in the activity of neurons in the hippocampus and entorhinal cortex underlie the ability to spatially navigate and remember information regarding where we are, Ekstrom said. Dr. O’Keefe’s groundbreaking work in the 70s ushered in decades of high-impact work elucidating how these cells change their firing pattern due to changes in spatial geometry, vestibular cues, and visual cues. In this way, place cells provide not just a code for navigation but for memory more generally. His work has also influenced our understanding of the human brain, where the existence of place cells have been confirmed in rare neurosurgical patients who explore virtual reality while undergoing brain recordings, by suggesting that place cells may be one of many different cellular mechanisms for coding the details of memories.
The Mosers’ work has similarly been highly influential in our understanding of navigation by suggesting that neurons in the entorhinal cortex code for spatial environments by firing in a regular, grid-like fashion as a rat explores a spatial environment. These cells differ, though, in several important ways from the place cells described by O’Keefe, in that they are less sensitive to changes in spatial geometry and provide a more detailed “metric” of space than place cells do. Recent work has also confirmed the existence of grid-cells in human neurosurgical patients; their integration into a larger memory system in humans is just beginning to be explored, including by work here at UC-Davis.
Recently I joined a large delegation from UC Davis, led by Chancellor Linda P.B. Katehi, at the 80th anniversary celebration of China’s Northwest Agricultural and Forestry University in Shaanxi province, including an international forum on the development of western China cosponsored by UC Davis. For all of us, the forum was a powerful reminder that western China is key to the future prosperity of that nation — much like California, which rose from obscurity to become the richest and most agriculturally productive state in the U.S.
Xi’an, the capital of Shaanxi province, was the beginning of the Silk Road, which opened up political and economic linkages between China and other civilizations. Western China has vast land area and undeveloped resources that will be critical for the future economic development of the country.
In terms of economic development over the past 30 years, eastern China is far ahead of western China, which now is home to 400 million people, including most of China’s poor communities. Seventy percent of those people are engaged in agriculture and have farm incomes less than one-third that of urban incomes. Solving these looming problems of the west will be key to China’s future.
This may seem a daunting task, but remember that just over 110 years ago California was considered a poor, desert region and yet it has since grown to become the richest state and number one agricultural producer in the nation. California and much of the American West prospered as infrastructure, market incentives and water were made available, and its agricultural development was accelerated by research, teaching and extension services provided by the University of California.
UC Davis and Northwest Agriculture and Forestry University recently agreed to work together to establish a joint research center on food safety. Through this and other initiatives, many of us at UC Davis are eager to partner with China and the Northwest Agriculture and Forestry University to help solve the agricultural, environmental and ecological challenges associated with the economic development of Western China.
Professor Colin Carter is an agricultural economist at UC Davis with roughly 30 years of research experience in China.
About one-fifth of the Earth’s atmosphere is oxygen, pumped out by green plants as a result of photosynthesis and used by most living things on the planet to keep our metabolisms running. But before the first photosynthesizing organisms appeared about 2.4 billion years ago, the atmosphere likely contained mostly carbon dioxide, as is the case today on Mars and Venus.
Over the past 40 years, researchers have thought that there must have been a small amount of oxygen in the early atmosphere. Where did this abiotic (“non-life”) oxygen come from? Oxygen reacts quite aggressively with other compounds, so it would not persist for long without some continuous source.
Now UC Davis graduate student Zhou Lu, working with professors in the Departments of Chemistry and of Earth and Planetary Sciences, has shown that oxygen can be formed in one step by using a high energy vacuum ultraviolet laser to excite carbon dioxide. (The work is published Oct. 3 in the journal Science).
“Previously, people believed that the abiotic (no green plants involved) source of molecular oxygen is by CO2 + solar light — > CO + O, then O + O + M — > O2 + M (where M represents a third body carrying off the energy released in forming the oxygen bond),” Zhou said in an email. “Our results indicate that O2 can be formed by carbon dioxide dissociation in a one step process. The same process can be applied in other carbon dioxide dominated atmospheres such as Mars and Venus.”
UC Davis chemists have shown how ultraviolet light can split carbon dioxide to form oxygen in one step. Credit: Zhou Lu
Zhou used a vacuum ultraviolet laser to irradiate CO2 in the laboratory. Vacuum ultraviolet light is so-called because it has a wavelength below 200 nanometers and is typically absorbed by air. The experiments were performed by using a unique ion imaging apparatus developed at UC Davis.
Such one-step oxygen formation could be happening now as carbon dioxide increases in the region of the upper atmosphere, where high energy vacuum ultraviolet light from the Sun hits Earth or other planets. It is the first time that such a reaction has been shown in the laboratory. According to one of the scientists who reviewed the paper for Science, Zhou’s work means that models of the evolution of planetary atmospheres will now have to be adjusted to take this into account.
Coauthors on the paper are, in the UC Davis Department of Chemistry, postdoctoral researcher Yih Chung Chang, Distinguished Professor Cheuk-Yiu Ng and Distinguished Professor emeritus William M. Jackson; and Professor Qing-Zhu Yin, Department of Earth and Planetary Sciences. The work was principally funded by NASA, NSF, and the U.S. Department of Energy.
Curiosity helps us learn about a topic, and being in a curious state also helps the brain memorize unrelated information, according to researchers at the UC Davis Center for Neuroscience. Work published Oct. 2 in the journal Neuron provides insight into how piquing our curiosity changes our brains, and could help scientists find ways to enhance overall learning and memory in both healthy individuals and those with neurological conditions.
“Our findings potentially have far-reaching implications for the public because they reveal insights into how a form of intrinsic motivation — curiosity — affects memory. These findings suggest ways to enhance learning in the classroom and other settings,” says first author Matthias Gruber, a postdoctoral researcher at the center.
Video: How curiosity changes the brain and enhances learning
Participants in the study first rated their curiosity about the answers to a series of trivia questions. Later, they had their brains scanned via functional magnetic resonance imaging while they learned the answers to these questions. First, they were presented with a selected trivia question and while they waited for the answer to pop up on the screen, they were shown a picture of a neutral, unrelated face.
Afterwards, participants performed a surprise recognition memory test for the presented faces, followed by a memory test for the answers to the trivia questions.
As might be expected, people were better at learning the trivia information when they were highly curious about it. More surprisingly, they also showed better learning of the unrelated faces that were shown while their curiosity was aroused. Information learned during a curious state was better retained over a 24-hour delay.
“Curiosity may put the brain in a state that allows it to learn and retain any kind of information, like a vortex that sucks in what you are motivated to learn, and also everything around it,” Gruber said.
Secondly, the investigators found that when curiosity is stimulated, there is increased activity in the brain circuit related to reward.
“We showed that intrinsic motivation actually recruits some of the same brain areas that are heavily involved in tangible, extrinsic motivation,” Gruber said. This reward circuit relies on dopamine, a chemical that relays messages between neurons.
The team also discovered that when learning was motivated by curiosity, there was increased activity in the hippocampus, a brain region that is important for forming new memories, as well as increased interactions between the hippocampus and the dopamine reward circuit.
Charan Ranganath is exploring the basis of memory.
“So curiosity recruits the reward system, and interactions between the reward system and the hippocampus seem to put the brain in a state in which you are more likely to learn and retain information, even if that information is not of particular interest or importance,” said Charan Ranganath, senior author, and Professor at the UC Davis Center for Neuroscience and Department of Psychology.
Brain circuits that rely on dopamine tend to decline in function with aging, or sooner in people with neurological or psychiatric disorders. Understanding the relationship between motivation and memory could stimulate new efforts to improve memory in the healthy elderly and new approaches for treating patients with memory disorders. And in the classroom or workplace, learning could be enhanced if teachers or managers can engage students’ and workers’ curiosity about something they are naturally motivated to learn.
Coauthors on the study were Gruber, Ranganath and research scientist Bernard Gelman. The work was supported by the National Institutes of Health, the Simon J. Guggenheim Foundation, and the Leverhulme Trust.