From a Student Competition to a Potential Treatment for Celiac Disease

Synthetic DNA Approach is Key to Startup’s New Drug

By Lisa Howard

The way Justin Siegel describes it, ordering synthetic DNA is almost as easy as ordering a pair of shoes online.

“You just type it in — or if the protein has been sequenced at one point, we can copy and paste — order it, and it shows up five days later.”

UC Davis chemist Justin Siegel is a co-founder of PvP Biologics. The company is developing a new treatment for celiac disease, an autoimmune disorder triggered by ingesting gluten. (UC Davis/Karin Higgins)

Wheat Gene Database is Tool for Improved Yield and Nutrition

By Ann Filmer

Plant scientists and wheat breeders now have a new tool to develop more nutritious and productive wheat varieties: A public online database of 10 million mutations in wheat genes. Scientists at UC Davis and three institutions in the UK created the database, which will allow scientists worldwide to study the function of every gene of wheat. The research will be reported in Proceedings of the National Academy of Sciences this week.

UC Davis Plant Sciences Professor, Jorge Dubcovsky is working to improve the yield and nutritional value of wheat, one of the world's most important crops.

UC Davis Plant Sciences Professor, Jorge Dubcovsky is working to improve the yield and nutritional value of wheat, one of the world’s most important crops.