Lab-grown Cartilage Transplant Eases Temporomandibular Joint Disease in Animal Model

A first-ever tissue implant to safely treat a common jaw defect, temporomandibular joint dysfunction, has been successfully tested in animals by researchers from UC Irvine and UC Davis.

“We were able to show that we could achieve exceptional healing of the TMJ area after eight weeks of treatment,” said UCI Distinguished Professor of biomedical engineering Kyriacos Athanasiou, senior author on the study, published Wednesday in Science Translational Medicine. Athanasiou, who joined UC Irvine last year after several years at UC Davis’ Department of Biomedical Engineering, has been working on the condition for nearly two decades.